General Information

  • ID:  hor004662
  • Uniprot ID:  O24572
  • Protein name:  CLAVATA3/ESR (CLE)-related protein ESR2-C
  • Gene name:  ESR2C
  • Organism:  Zea mays (Maize)
  • Family:  CLV3/ESR signal peptide family
  • Source:  Plant
  • Expression:  [ESR2Cp]: Expressed specifically in the embryo surrounding region at the micropylar end of the seed endosperm at early stages (4 to 7 days after pollination, DAP) and ever-decreasing parts of the suspensor at subsequent stages. |[ESR2Cp]: Seed endosperm.
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Zea (genus), Tripsacinae (subtribe), Andropogoneae (tribe), Andropogonodae, Panicoideae (subfamily), PACMAD clade, Poaceae (family), Poales (order), commelinids, Petrosaviidae (subclass), Liliopsida, Mesangiospermae, Magnoliopsida (class), Spermatophyta, Euphyllophyta, Tracheophyta, Embryophyta, Streptophytina (subphylum), Streptophyta (phylum), Viridiplantae (kingdom), Eukaryota (superkingdom), cellular organisms
  • GO MF:  GO:0033612 receptor serine/threonine kinase binding
  • GO BP:  GO:0030154 cell differentiation; GO:0045168 cell-cell signaling involved in cell fate commitment
  • GO CC:  GO:0005576 extracellular region; GO:0048046 apoplast

Sequence Information

  • Sequence:  TRTDDKPGVNRNMEMQQQQGGFIGHRPRLASFNRASKQLDREKRPVPSGPDPIHHSIPSHAPQHPPSYGKAPYEDDKSIASPGLSNLIGPPPFLDRY
  • Length:  97
  • Propeptide:  TRTDDKPGVNRNMEMQQQQGGFIGHRPRLASFNRASKQLDREKRPVPSGPDPIHHSIPSHAPQHPPSYGKAPYEDDKSIASPGLSNLIGPPPFLDRY
  • Signal peptide:  NA
  • Modification:  T47 Hydroxyproline;T50 Hydroxyproline
  • Glycosylation:  T50 O-linked (Ara...) hydroxyproline
  • Mutagenesis:  NA

Activity

  • Function:  Extracellular signal peptide that regulates cell fate.
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-O24572-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    AF-O24572-F1.pdbhor004662_AF2.pdbhor004662_ESM.pdb

Physical Information

Mass: 1250251 Formula: C472H734N146O142S2
Absent amino acids: CW Common amino acids: P
pI: 10 Basic residues: 18
Polar residues: 26 Hydrophobic residues: 20
Hydrophobicity: -113.51 Boman Index: -26035
Half-Life: 7.2 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 51.34
Instability Index: 4947.22 Extinction Coefficient cystines: 4470
Absorbance 280nm: 46.56

Literature

  • PubMed ID:  NA
  • Title:  NA